From East of Downtown:
Head West on Freeway 10
Take Freeway 101
Exit on Alameda St.
Turn left on Los Angeles St.
From Los Angeles Street turn right on Winston St.

From West of Downtown:

Head East on Freeway 10
Take 101 Freeway North 
Take 4th St. exit
Turn right on Los Angeles St. 

From North of Downtown:
Head South on 101 Freeway
Take Los Angeles St. exit
Turn right onto Los Angeles St.
Turn right to Winston St.

From South of Downtown:
Head North on Freeway 5
Take 101 Freeway North
Take 4th St. exit
Turn left on traffic light
Turn left on Los Angeles St.
Turn right to Winston St.